Progress on vitamin D in the prevention and treatment of colorectal cancer and its supplementation applications
10.16352/j.issn.1001-6325.2025.03.0404
- VernacularTitle:维生素D在防治结直肠癌及补充应用的研究进展
- Author:
Shujun ZHANG
1
;
Tiantian LI
;
Mingliang ZHONG
;
Jian ZHANG
;
Xinmin DONG
Author Information
1. 内蒙古医科大学 第一临床医学院 放射肿瘤学系,内蒙古 呼和浩特 010000
- Keywords:
vitamin D;
colorectal cancer;
dosage of vitamin D
- From:
Basic & Clinical Medicine
2025;45(3):404-408
- CountryChina
- Language:Chinese
-
Abstract:
Colorectal cancer is one of the common malignant tumors in digestive system,because of its incidence and mortality rates rising annually in China,seriously threating to people's lives and health.Vitamin D plays an im-portant role in inhibiting colorectal cancer by suppressing tumor cell proliferation,promoting tumor cell apoptosis,inhibiting tumor cell migration,invasion,and angiogenesis and also,enhancing the body's immune system.This article summarizes and analyzes the specific mechanisms by which vitamin D inhibits the occurrence and develop-ment of colorectal cancer,and discusses the current progress in research on vitamin D supplementation,providing new references for the early prevention and adjuvant treatment of colorectal cancer.
