Progress on dietary therapy for gout and hyperuricemia

VernacularTitle:饮食治疗痛风与高尿酸血症的研究进展
Author: Lei JIN ¹ ; Qianqian WU ; Xiaomin ZHANG ; Jie GUO ; Feng WANG
Author Information

1. 上海交通大学医学院附属第一人民医院风湿免疫与变态反应科,上海 200080
Keywords: gout; hyperuricemia; dietary factor; nutrition; body mass index
From: Basic & Clinical Medicine 2025;45(3):382-389
CountryChina
Language:Chinese
Abstract: This review briefs the anti-hyperuricemia(HUA)mechanism of nutrition targeting the gut,such as the gut microbiota promoting the catabolism of purine and uric acid(UA),and increased its metabolites like uric acid.The review also summarizes the probiotics and prebiotics that have the effect of lowering uric acid targeting at the gut,providing reference and guidance for further research.In addition,this paper reviews the effects of various di-ets,such as the dietary approaches to stop hypertension(DASH)diet,the Mediterranean diet,and the low-purine diet,as well as the effects of individual foods including alcohol,coffee and tea,cherries,dairy products,fructose,and vitamin C on hyperuricemia and gout outcomes.