Mechanisms and therapeutic strategies of sepsis-associated cytokine storm
10.16352/j.issn.1001-6325.2025.02.0263
- VernacularTitle:脓毒症相关细胞因子风暴的机制与治疗策略
- Author:
Tingting WANG
1
;
Haidong QIN
Author Information
1. 南京医科大学附属南京医院 急诊科,江苏 南京 210006
- Keywords:
sepsis;
cytokine storm;
innate immunity;
systemic inflammatory response syndrome;
multiple organ dysfunction syn-drome
- From:
Basic & Clinical Medicine
2025;45(2):263-267
- CountryChina
- Language:Chinese
-
Abstract:
Sepsis is one of the most common critical conditions in clinical practice,with a persistently high mortali-ty rate.As the core pathological mechanism of sepsis,cytokine storm,the continuous activation of the immune sys-tem and the disordered release of a large number of cytokines cause severe damage to the patient's tissues and or-gans,leading to systemic inflammatory response syndrome and even multiple organ dysfunction syndrome,posing a significant threat to patient health.Therefore,this article reviews the role of cytokine storm in sepsis and current therapeutic strategies.
