Role of transmembrane protein 33 in tumorigenesis and development
10.16352/j.issn.1001-6325.2025.02.0258
- VernacularTitle:跨膜蛋白33在肿瘤发生发展中的作用
- Author:
Haijun LOU
1
;
Menggen MENG
;
Zhenyu ZHANG
;
Zhuoyun TONG
;
Muli WUDU
Author Information
1. 新疆医科大学 基础医学院 病理教研室,新疆 乌鲁木齐 830017
- Keywords:
transmembrane protein 33;
tumor development;
tumor metastasis;
biomarker;
therapeutic target
- From:
Basic & Clinical Medicine
2025;45(2):258-262
- CountryChina
- Language:Chinese
-
Abstract:
Transmembrane protein 33(TMEM33)is up-regulated in the majority of cancers.To change the expression of TMEM33 can significantly affect the proliferation,migration,and invasion of renal and cervical cancer cells.Its mechanisms of action may involve four aspects:1)participation in lipid metabolism;2)regu-lation of endoplasmic reticulum;3)regulation of intracellular calcium homeostasis;4)participation in angio-genesis.
