Research progress in the characterization of amino acid metabolism in frailty patients
10.16352/j.issn.1001-6325.2025.02.0253
- VernacularTitle:衰弱患者氨基酸代谢特征的研究进展
- Author:
Huishan WU
1
;
Yingping LIAO
;
Meng LI
Author Information
1. 浙江中医药大学 第二临床医学院,浙江 杭州 310053
- Keywords:
frailty;
amino acid metabolism;
diagnose
- From:
Basic & Clinical Medicine
2025;45(2):253-257
- CountryChina
- Language:Chinese
-
Abstract:
Frailty is a complex aging syndrome characterized by diminished strength and physiological dysfunction.Early diagnosis of frailty is of great value in helping the elderly to improve the quality of life.However,specific bio-logical markers to diagnose frailty are still lacking.In recent years,moderate protein intake has been shown to be an effective intervention in the management of frailty in older adults,and the relationship between frailty and amino acid metabolism has received widespread attention.This review discusses recent advances in the study of the mecha-nisms by which amino acid metabolism affects frailty and provide new ideas for searching specific biomarkers of frailty.