Role of G protein-coupled receptor 120 in respiratory diseases
10.16352/j.issn.1001-6325.2025.02.0244
- VernacularTitle:G蛋白偶联受体120在呼吸系统疾病中的作用
- Author:
Yanyan ZHAO
1
;
Lijun ZHANG
;
Xiaochun ZHANG
;
Xiangyan LIANG
;
Yufeng ZHAO
Author Information
1. 西安医学院 基础医学研究所,陕西 西安 710021
- Keywords:
GPR120;
respiratory system;
airway epithelium
- From:
Basic & Clinical Medicine
2025;45(2):244-248
- CountryChina
- Language:Chinese
-
Abstract:
G protein-coupled receptor 120(GPR120)is one of the membrane receptors for long chain free fatty acids and is distributed in alveolus macrophages and airway epithelial Club cells.GPR120 activation alleviates the inflammation of respiratory tract,improves airway hyper-responsiveness,stimulates proliferation of Club cells and promotes the repair of respiratory epithelium,which may attenuate asthma and acute lung injury.
