Pathogenesis of acute lung injury of the newborns
10.16352/j.issn.1001-6325.2025.01.0135
- VernacularTitle:新生儿急性肺损伤的发病机制
- Author:
Ruotong YANG
1
;
Guoying ZHAO
;
Hao WANG
Author Information
1. 滨州医学院附属医院 儿科,山东 滨州 256600
- Keywords:
fetus/newborns infant;
acute lung injury;
acute respiratory distress syndrome;
pathogenesis
- From:
Basic & Clinical Medicine
2025;45(1):135-139
- CountryChina
- Language:Chinese
-
Abstract:
Due to factors such as narrow airways and incomplete development of alveoli,newborns are prone to acute lung injury(ALI),which may progress to severe condition known as acute respiratory distress syndrome(ARDS).The mechanisms underlying the occurrence and progression of ALI in newborns involve various as-pects,including oxidative stress,iron death,inflammatory response and reduction of pulmonary surfactant.Further research into these mechanisms is expected to provide strategy to guide clinical management in novo pathway.
