Effects of heavy metal exposure on bronchial asthma in children
10.16352/j.issn.1001-6325.2025.01.0121
- VernacularTitle:重金属暴露对儿童支气管哮喘的影响
- Author:
Beilei WANG
1
;
Xingyue SU
;
Xiang MA
Author Information
1. 山东大学附属儿童医院 呼吸科,山东 济南 250022
- Keywords:
bronchial asthma;
child;
heavy metals
- From:
Basic & Clinical Medicine
2025;45(1):121-125
- CountryChina
- Language:Chinese
-
Abstract:
Bronchial asthma(asthma)is a chronic respiratory disease with complex etiology.Because of increasing application of heavy metals in human society,human exposure to heavy metals is a challenge to public health.This review summarizes recent studies to evaluate the effects and mechanisms of heavy metal exposure on asthma in chil-dren.Results of researches have showed that heavy metal exposure resulted in production of reactive oxygen species(ROS)to induce oxidative stress,enhancement of the level of inflammatory cytokines,promoting airway inflamma-tory response and airway remodeling and thus aggravating the occurrence and development of asthma.Further study on these effects may lead to the development of clinical guidance for asthma management.
