Progress of researches on the differential diagnosis of Pneumocystis jiroveci infection and colonization
10.16352/j.issn.1001-6325.2025.01.0116
- VernacularTitle:鉴别肺孢子菌感染与定植的研究进展
- Author:
Xingchen LI
1
;
Jin TONG
Author Information
1. 重庆医科大学附属第二医院 呼吸与危重症医学科,重庆 400072
- Keywords:
Pneumocystis jroveci;
Pneumocystis jroveci pneumonia;
colonization;
diagnosis;
differential diagnosis
- From:
Basic & Clinical Medicine
2025;45(1):116-120
- CountryChina
- Language:Chinese
-
Abstract:
Pneumocystis jiroveci(PJ)is an atypical conditional pathogenic fungus.PJ colonization is a potential risk factor for Pneumocystis jiroveci pneumonia(PJP).Active identification of PJ colonization or infection is conducive to rational use of antibiotics.Although serum G test combined with molecular detection technology,peripheral blood CD4+T level and independent characterization of trophozoites and cysts by transcriptome sequencing technology may support identifying PJ colonization and diagnosis of infection,unified standards have not yet been established.Based on the pathogenic characteristics and pathogenic mechanism of PJ,clinical characteristics and diagnostic methods of PJP,this paper reviews the progress of differential diagnosis of PJ infection and colonization,so as to provide more objective and comprehensive differential strategy for clinical diagnosis and treatment.
