A Study of Prognostic Factors of Stage Ⅳ Epithelial Ovarian Cancer

VernacularTitle:Ⅳ期上皮性卵巢癌的生存率及其影响因素分析
Author: Jin GAO ¹ ; Ai ZHENG ; Wenxian CHEN ; Zhilan PENG ; Zheyi CAO
Author Information

1. The Second Affiliated Hospital WCUMS
From: Journal of Sichuan University (Medical Sciences) 2001;32(2):309-312
CountryChina
Language:Chinese
Abstract: Objective　To determine the effects of treatments for stage Ⅳ epidermal ovarian cancer and detect the prognostic factors. Methods　31 cases primarily treated in our hospital from 1990 to 1998 were analyzed retrospectively. Results　Univariate analysis showed that the number of courses of chemotherapy, the size of residual disease, the histologic cell type, and the metastatic site were the significant prognostic factors（P＜0.05）. Cox proportional hazard model confirmed that two factors(the size of residual lesion ≤2 cm and the cycles of chemotherapy ≥8 decreased the death odds ratio by 0.28 and 0.72 respectively. Three factors (lack of operation, presence of supraclavicular lymph node involvement and liver involvement) increased the death odds ratio by 14.25 times, 11.44 times and 1.85 times respectively (P＜0.05). Conclusion　Surgical debulking, aggressive and appropriate chemotherapy are important measures to improve survival rate for patients with stage Ⅳ epithelial ovarian cancer.