The Effect of AG490 on NK Activity and Lymphocyte Transformation of PBMC
10.3969/j.issn.1672-173X.2001.02.018
- VernacularTitle:AG490对人外周血NK细胞活性及淋巴细胞转化功能的影响
- Author:
Rong WANG
1
;
Ping ZHANG
;
Dapeng WEI
;
Zongrong ZHAO
Author Information
1. School of Basic Medical Sciences
- From:
Journal of Sichuan University (Medical Sciences)
2001;32(2):219-221
- CountryChina
- Language:Chinese
-
Abstract:
Objective To examine the effect of AG490 on NK activity and lymphocyte transformation. Methods Using MTT colorimetry to detect cell survival, NK activity and cell proliferation. Results AG490 inhibited IL-2 and PHA induced peripheral blood mononuclear cell proliferation, and it inhibited NK activation. Conclusion As an inhibitor of JAK, AG490 can influence the function of normal cells.
