Plaque characteristics evaluated by intravascular ultrasound in postmenopausal women with coronary artery disease and their impacts on stent implantation
10.3969/j.issn.1009-0754.2025.11.016
- VernacularTitle:基于冠状动脉血管内超声评估的斑块性质对绝经女性冠心病患者冠状动脉支架置入的影响分析
- Author:
Haiou LI
1
;
Dongyan ZHANG
;
Weiwei ZHAO
Author Information
1. 065700 河北 廊坊,廊坊市第四人民医院心内科
- Keywords:
Intravascular ultrasound;
Coronary artery disease;
Plaque characteristics;
Stent placement;
Menopausal status
- From:
Journal of Navy Medicine
2025;46(11):1157-1161
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the plaque characteristics evaluated by intravascular ultrasound(IVUS)in perimenopausal women with coronary artery disease(CAD)and their impacts on the outcomes of stent implantation.Methods A total of 169 female CAD patients who were admitted to the Fourth People's Hospital of Langfang City from March 2021 to March 2023 were selected as research objects.All the patients underwent coronary angiography(CAG)and IVUS to identify plaque characteristics.Based on the plaque stability,the patients were assigned to stable plaque group(n=105)or unstable plaque group(n=64).Clinical data,IVUS parameters,coronary stent placement,and the incidence of major adverse cardiac events(MACE)were compared between the two groups.Results The plaque burden in the unstable plaque group was higher than that in the stable plaque group,while the minimal lumen area in the unstable plaque group was lower than that in the stable plaque group(P<0.05).The incidences of thrombosis,plaque rupture,and calcification in the unstable plaque group were higher than those in the stable plaque group(P<0.05).The stent placement rate and achievement rate in the unstable plaque group were higher than those in the stable plaque group(P<0.05).Kaplan-Meier survival analysis showed that the incidence of MACE in the unstable plaque group was significantly higher than that in the stable plaque group(HR=2.257,95%CI:1.184-4.303,log-rank P=0.007).Conclusion IVUS shows high value in evaluating plaque characteristics in perimenopausal women with CAD.It can be used as an important tool to optimize treatment strategies.
