Clinical outcomes of low temperature plasma radiofrequency ablation combined with nasal irrigation in treatment of allergic rhinitis with nasal septal deviation
10.3969/j.issn.1009-0754.2025.08.008
- VernacularTitle:低温等离子射频消融术联合鼻腔冲洗治疗伴鼻中隔偏曲的变应性鼻炎的临床疗效观察
- Author:
Peipei YANG
1
;
Haiqing ZHANG
;
Silin CHEN
;
Xuping WANG
Author Information
1. 210046 江苏 南京,泰康仙林鼓楼医院耳鼻喉科
- Keywords:
Allergic rhinitis;
Nasal septal deviation;
Low temperature plasma radiofrequency ablation;
Quality of life
- From:
Journal of Navy Medicine
2025;46(8):782-786
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the clinical efficacy of low temperature plasma radiofrequency ablation(RFA)combined with nasal irrigation in the treatment of allergic rhinitis(AR)with nasal septal deviation.Methods A total of 120 AR patients with nasal septal deviation who were diagnosed and treated in Taikang Xianlin Drum Tower Hospital from August 2018 to December 2022 were selected as research objects.They were assigned to observation group or control group according to random number table method,with 60 cases in each group.The control group received nasal irrigation,and the observation group received low temperature plasma RFA and nasal irrigation.The efficacy,immunity,inflammation,quality of life,safety and prognosis were compared between the two groups.Results The observation group had better curative effect than the control group(P<0.05).The natural killer(NK)cells were increased,and the levels of immunoglobulin G(IgE),thymic stromal lymphopoietin(TSLP),hypoxia-inducible factor-1(HIF-1)and fractional exhaled nitric oxide(FeNO)were decreased in both groups after treatment.The level of NK cells in the observation group was higher than that in the control group after treatment,and the levels of IgE,TSLP,HIF-1,and FeNO in the observation group were lower than those in the control group(P<0.05).After treatment,the rhinoconjunctivitis quality of life questionnaire(RQLQ)scores decreased in both groups,and the scores in the observation group were lower than those in the control group(P<0.05).There was no significant difference in safety between the two groups(P>0.05).The control group had higher recurrence rate than the observation group(P<0.05).Conclusion Low temperature plasma RFA combined with nasal irrigation can effectively improve the immune function and inflammation of AR patients with nasal septal deviation,thereby improving the efficacy and quality of life,and reducing the recurrence rate,with high safety.
