Predictive value of P(cv-a)CO2/C(a-cv)O2 ratio in volume assessment after fluid resuscitation in hemorrhagic shock patients
10.3969/j.issn.1009-0754.2025.07.017
- VernacularTitle:P(cv-a)CO2/C(a-cv)O2比值在失血性休克患者液体复苏后容量评估中的预测价值
- Author:
Weihong XIE
1
;
Danchun LIN
;
Guoyuan LIANG
;
Peiyang ZENG
Author Information
1. 523000 广东东莞,东莞市第八人民医院
- Keywords:
Hemorrhagic shock;
Central venous-arterial carbon dioxide partial pressure difference/arterial-central venous oxygen content difference;
Lactate concentration;
Lactate clearance rate
- From:
Journal of Navy Medicine
2025;46(7):733-738
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between the changes in P(cv-a)CO?/C(a-cv)O? ratio and hypoxic states in patients with hemorrhagic shock after effective fluid resuscitation.Methods Thirty hemorrhagic shock patients who were admitted to ICU Dongguan Eighth People's Hospital from October 1,2021 to November 30,2023 were selected as research objects.All the patients underwent early fluid resuscitation.Arterial and central venous blood gas analysis was performed,and arterial lactate concentration was measured before resuscitation,and at 2 h,6 h,12 h,and 24 h after resuscitation.The P(cv-a)CO2/C(a-cv)O2,the gradient of P(cv-a)CO2/C(a-cv)O2,and lactate clearance rate were calculated.Results There was a positive correlation between the P(cv-a)CO?/C(a-cv)O? ratio and lactate concentration,as well as between the gradient of P(cv-a)CO?/C(a-cv)O? and lactate clearance rate at each time point(P<0.05).There were significant differences in the P(cv-a)CO?/C(a-cv)O?,gradient of P(cv-a)CO?/C(a-cv)O?,and lactate clearance rate after resuscitation among patients with different prognoses(P<0.05).Conclusion The P(cv-a)CO2/C(a-cv)O2 and its change rate,as well as lactate clearance rate,can predict the prognosis of patients with hemorrhagic shock.
