Effect of spinal cord electrical stimulation on diabetic peripheral neuropathy
10.3969/j.issn.1009-0754.2025.07.011
- VernacularTitle:脊髓电刺激治疗糖尿病末梢神经病变的临床研究
- Author:
Xiaoli XIE
1
;
Shengxian SU
;
Yuanfeng YANG
;
Zhiguang LIN
;
Junlin WEN
Author Information
1. 528400 广东 中山,中山市人民医院疼痛医学科
- Keywords:
Spinal cord electrical stimulation;
Diabetic peripheral neuropathy;
Hemorheology;
Quality of life;
Sleep quality
- From:
Journal of Navy Medicine
2025;46(7):698-703
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of spinal cord electrical stimulation on diabetic peripheral neuropathy.Methods A total of 120 patients with diabetic peripheral neuropathy were randomly assigned to three groups,with 40 cases in each group.Group A was treated with pregabalin.Group B received radiofrequency therapy of lumbar sympathetic ganglion.Group C was treated with spinal cord electrical stimulation.The treatment course was six months.Pain,EMG parameters,hemorheology indexes,quality of life,sleep quality,and HbA1c were compared among groups.Results Group C had higher therapeutic effective rate than groups A and B(P<0.05)after 6 months of treatment.After 1 week,3 months,6 months and 12 months of treatment,the visual analogue scale(VAS)scores and HbA1c levels of group C were lower than those of groups A and B(P<0.05).After 6 months of treatment,the motor nerve and sensory nerve conduction velocities of the median nerve and peroneal nerve in group C were higher than those in groups A and B(P<0.05).After 6 months of treatment,the whole blood viscosity and capillary plasma viscosity of group C were lower than those of groups A and B(P<0.05).After 6 months of treatment,the 36-item short form health survey(SF-36)score of group C was higher than that of groups A and B,and the Pittsburgh sleep quality Index(PSQI)score of group C was lower than that of groups A and B(P<0.05).The incidence of adverse reactions in group C was lower than that in groups A and B(P<0.05).Conclusion Compared with drugs and lumbar sympathetic ganglion radiofrequency therapy,spinal cord electrical stimulation has a better efficacy in the treatment of diabetic peripheral neuropathy.It can continuously relieve neuropathic pain,increase the velocity of motor and sensory nerve conduction,improve the hemorheology,HbA1c levels,quality of life and sleep quality,and has high safety and significant clinical value.
