Efficacy of iRoot SP single-tip filling technique in the treatment of dental pulp disease and its influence on serum IL-1β,IL-4 and TNF-α
10.3969/j.issn.1009-0754.2025.07.010
- VernacularTitle:iRoot SP单尖法充填技术治疗牙体牙髓病的疗效及对血清IL-1β、IL-4、TNF-α水平的影响
- Author:
Yang ZONG
1
;
Zhigang ZHANG
;
Hua HE
Author Information
1. 402360 重庆,重庆市大足区人民医院口腔科
- Keywords:
Dental pulp disease;
iRoot SP sealer;
Root canal filling;
Single-tip method;
Inflammatory factors
- From:
Journal of Navy Medicine
2025;46(7):693-697
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the application of iRoot SP single-tip filling technique in the treatment of dental pulp disease and its influence on serum inflammatory factors.Methods A total of 86 patients with dental pulp disease who were admitted to Dazu District People's Hospital from July 2022 to December 2022 were selected and assigned to observation group or control group according to a random number table,with 43 cases in each group.The observation group underwent root canal filling by iRoot SP single-tip method,and the control group was given root canal filling by iRoot SP cold lateral condensation.The filling effect,serum levels of interleukin(IL)-1β,IL-4,and tumor necrosis factor-α(TNF-α)before and after treatment,and short-term efficacy were compared between the two groups.Results The exact filling rate in the observation group was higher than that in the control group(93.02%vs.76.76%,P<0.05).The time of root canal filling in the observation group was shorter than that in the control group(P<0.05),but there was no significant difference in the proportion of filling area between the two groups(P>0.05).After treatment,serum IL-4 level was increased,while IL-1β and TNF-α were decreased in both groups(P<0.05);observation group had higher IL-4 level and lower IL-1β and TNF-α levels than control group(P<0.05).After 3 months of treatment,no significant difference was found in the total effective rate between the two groups(P>0.05).Conclusion iRoot SP single-tip filling technique can shorten the filling time,increase the exact filling rate,and reduce the inflammation levels in the treatment of dental pulp disease.In clinical practice,the appropriate technique should be selected according to patient's condition.
