Predictive value of uterine artery Doppler parameters combined with cerebral placental ratio for late-onset fetal growth restriction
10.3969/j.issn.1009-0754.2025.05.014
- VernacularTitle:子宫动脉超声参数联合脑胎盘率检测对晚发型胎儿生长受限的预测价值
- Author:
Xiaoling MAO
1
;
Kun WU
;
Ju GONG
Author Information
1. 214400 江苏 无锡,江阴市中医院妇产科
- Keywords:
Uterine artery Doppler;
Cerebral placental ratio;
Late-onset fetal growth restriction;
Prognostic assessment
- From:
Journal of Navy Medicine
2025;46(5):484-488
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the application value of uterine artery Doppler parameters combined with cerebral placental ratio(CPR)in predicting late-onset fetal growth restriction(FGR).Methods A total of 82 pregnant women with singleton pregnancy of FGR who were admitted to Jiangyin Hospital of Traditional Chinese Medicine from May 2021 to May 2023 were enrolled.And 60 healthy pregnant women with singleton pregnancy who underwent physical examinations during the same period were enrolled as control.All participants underwent arterial ultrasound examination,and CPR was measured.The uterine artery Doppler parameters and CPR were compared between the FGR group and control group,and their correlation with the disease was analyzed.The predictive efficacy of combined detection was assessed through receiver operator characteristic(ROC)curve.Results The systolic peak velocity/end diastolic velocity(S/D),resistance index(RI),and pulsatility index(PI)of the uterine artery and umbilical artery(UA)in the FGR group were higher than those in the control group,whereas the S/D,RI,and PI of the middle cerabral artery(MCA)and CPR in the FGR group were lower than those in the control group(P<0.05).Spearman correlation analysis showed that the S/D,RI,and PI of the uterine artery and UA were positively correlated with late-onset FGR,and the S/D,RI,and PI of the MCA and CPR were negatively correlated with late-onset FGR(P<0.05).ROC curve analysis indicated that the AUC for predicting late-onset FGR by combining uterine artery Doppler parameters with CPR was 0.925,with a sensitivity of 79.3%and a specificity of 88.3%.Conclusion The uterine artery Doppler parameters combined with CPR can effectively predict late-onset FGR,providing significant clinical value in early identification of high-risk pregnant women and guiding clinical interventions.
