Quantitative parameters of dual-energy CT in predicting the severity of acute pancreatitis
10.3969/j.issn.1009-0754.2025.03.019
- VernacularTitle:双能量CT定量参数测定预测急性胰腺炎的严重程度
- Author:
Xiao LIU
1
;
Hang YU
Author Information
1. 200433 上海,海军军医大学第一附属医院急诊科
- Keywords:
Acute pancreatitis;
Dual-energy CT;
Severity;
Quantitative parameters;
Iodine concentration
- From:
Journal of Navy Medicine
2025;46(3):302-306
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the value of quantitative parameters of dual-energy CT in predicting the severity of acute pancreatitis(AP).Methods A retrospective analysis was conducted on 65 patients who were diagnosed with AP and underwent pancreatic dual-energy CT at the First Affiliated Hospital of Naval Medical University from July 2022 to July 2023.According to the Atlanta classification,the patients were assigned to mild,moderate,or severe groups.On the images of portal venous phase,the regions of interest(ROIs)in the head,body,and tail of the pancreas,as well as in the abdominal aorta were delineated by DECT multiparameter post-processing techniques.The iodine concentration of ROIs,normalized iodine concentration(NIC),and CT values were measured.Pearson correlation analysis was used to analyze the correlation between these quantitative parameters and scoring systems of AP severity(acute physiology and chronic health evaluation[APACHE]Ⅱ,Marshall's score,and Ranson's score).Receiver operator characteristic(ROC)curve was used to evaluate the effectiveness of quantitative parameters in predicting AP severity.Results There were 26 patients with mild AP,20 with moderate AP,and 19 with severe AP.There was no significant difference in average CT value between groups(P=0.056),but there were significant differences in iodine concentration and NIC(P＜0.001).With the increase of the severity of AP,iodine concentration and NIC showed a downward trend.Among all quantitative parameters,iodine concentration had strong correlations with APACHE Ⅱscore,Marshall's score,and Ranson's score,especially with APACHE Ⅱscore(r=-0.728,P＜0.001).Iodine concentration had a good predictive value for severe pancreatitis,with an area under curve of 0.845(95％CI:0.746-0.944),a threshold of 16.05 mg/ml,a sensitivity of 0.737,and a specificity of 0.844.Conclusion Iodine concentration in dual-energy CT can effectively predict the severity of AP and provide guidance for clinical treatment.
