Clinical efficacy of percutaneous microwave ablation in the treatment of benign cystic/solid thyroid nodules
10.3969/j.issn.1009-0754.2024.11.013
- VernacularTitle:经皮微波消融治疗囊实性良性甲状腺结节的临床疗效评估
- Author:
Ziwei LIU
1
;
Huafeng PAN
Author Information
1. 430081 湖北武汉,武汉科技大学医学院
- Keywords:
Benign cystic/solid thyroid nodules;
Ultrasonic guidance;
Microwave ablation;
Open surgery
- From:
Journal of Navy Medicine
2024;45(11):1163-1166
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical efficacy of ultrasound-guided percutaneous microwave ablation in the treatment of benign cystic/solid thyroid nodules.Methods A total of 98 patients with benign cystic/solid thyroid nodules who were treated in the Puren Hospital affiliated to Wuhan University of Science and Technology from January 2018 to July 2021 were selected as research objects.They were divided into two groups according to different treatment methods.There were 48 patients in the microwave ablation group and 50 patients in the open operation group.The operation time,hospital stay,intraoperative bleeding,inflammatory reaction indexes(C-reactive protein[CRP],interleukin 6[IL-6])one day after surgery,thyroid function indexes(FT3,FT4,and thyroid-stimulating hormone),postoperative complications,and recurrence rate during one-year follow-up were compared between the two groups.The nodule size and volume reduction rate were calculated at 6 and 12 months after operation.Results The intraoperative bleeding,operation time and length of hospital stay in the microwave ablation group were significantly less than those in the open operation group([1.65±0.64]ml vs[18.60±5.79]ml,[23.54±5.68)]min vs[99.30±17.18]min,[2.94±0.56]d vs[8.06±1.38]d).The levels of CRP and IL-6 increased after surgery in both groups,but the levels of CRP and IL-6 in the microwave ablation group were significantly lower than those in the open operation group(P<0.05).The incidence of hypothyroidism and complications in the microwave ablation group were significantly lower than those in the open operation group one day after operation(8.33%vs 64.00%,10.42%vs 66.00%).The recurrence rate in the microwave ablation group(12.50%)was higher than that in the open surgery group(10.00%)during one-year follow-up,with no significant difference(P=0.76).At 6 and 12 months after treatment,the size of the nodules was observed by ultrasound.The volume of the nodules in the microwave ablation group was reduced to(1.77±0.67)cm3 and(0.93±1.01)cm3,and the reduction rates of the nodules were(75.83±9.07)%and(88.38±11.89)%,respectively.Conclusion Compared with open surgery,ultrasound-guided percutaneous microwave ablation for benign cystic/solid thyroid nodules has shorter operation time,less trauma,fewer complications,less impact on thyroid function,and faster recovery.It is worthy of clinical application.
