Effect of soft channel minimally invasive puncture hematoma evacuation on hypertensive intracerebral hemorrhage based on intracranial pressure and blood-brain barrier index
10.3969/j.issn.1009-0754.2024.09.013
- VernacularTitle:基于颅内压和血脑屏障指数评估软通道微创穿刺血肿清除术治疗高血压脑出血的疗效
- Author:
Jufen ZHANG
1
;
Suqin WANG
;
Yan WU
;
Jinxu ZHOU
Author Information
1. 214000 江苏无锡,联勤保障部队第九〇四医院神经外科
- Keywords:
Hypertensive intracerebral hemorrhage;
Soft channel minimally invasive puncture hematoma evacuation;
Intracranial pressure;
Blood brain barrier index;
Efficacy
- From:
Journal of Navy Medicine
2024;45(9):946-949
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the efficacy of soft channel minimally invasive puncture hematoma evacuation in treatment of hypertensive intracerebral hemorrhage based on intracranial pressure and blood-brain barrier index.Methods A total of 78 patients with hypertensive intracerebral hemorrhage who were admitted to No.904 Hospital of Joint Logistics Support Force of PLA from February 2019 to September 2021 were enrolled and divided into two groups according to different treatment methods.Control group(n=35)received craniotomy,and observation group(n=43)received soft channel minimally invasive puncture hematoma evacuation.Operation related indexes(operation time,intraoperative blood loss,and drainage time),intracranial pressure,blood-brain barrier index and therapeutic effect were compared between two groups.Results The observation group had shorter operation time,shorter drainage time and less intraoperative blood loss than the control group(P<0.05).Intracranial pressure at 24 h postoperatively was lower than that at the end of surgery in both groups(P<0.05).Intracranial pressure at the end of surgery and 24 h postoperatively in the observation group was lower than those in the control group(P<0.05).The blood-brain barrier index was decreased in both groups after surgery,and the index in the observation group was lower than that in the control group(P<0.05).The overall efficacy rate of the observation group was significantly higher than that of the control group(93.02%vs 74.29%,P<0.05).Conclusion Soft channel minimally invasive puncture hematoma evacuation can effectively reduce the intracranial pressure and blood-brain barrier index in patients with hypertensive intra cerebral hemorrhage,with shorter operation time and less intraoperative bleeding.It can be used for preferred surgical procedure for hypertensive intra cerebral hemorrhage.