Experimental study on the prevention and treatment of motion sickness by acupuncture at Neiguan
10.3969/j.issn.1009-0754.2024.04.011
- VernacularTitle:针刺内关穴防治晕动病的实验研究
- Author:
Jingjing FANG
1
;
Yujia JIANG
;
Chaoyue SUN
;
Mengcheng CAI
;
Yanli YOU
Author Information
1. 200433 上海,海军军医大学学员二队
- Keywords:
Motion sickness;
Acupuncture;
Point PC6(Neiguan);
Mice
- From:
Journal of Navy Medicine
2024;45(4):366-370
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the therapeutic effect of acupuncture at Neiguan point(PC6),acupuncture on the upper limbs and traditional medication for motion sickness.Methods Totally 30 male KM mice were randomly divided into 5 groups(n=6):blank control group,model group(acceleration exposure),acupuncture PC6 group(acupuncture at PC6+acceleration exposure),acupuncture upper limbs group(acupuncture of the arm except PC6+acceleration exposure)and traditional medicine group(difenidol administered intragastrically+acceleration exposure).The motion sickness index(MSI)and the serum levels of serotonin(5-HT),adrenaline,glucagon,insulin and blood glucose were detected.Results MSI and serum 5-HT,adrenaline,glucagon,insulin and blood glucose levels in the model group were significantly higher than those in the blank control group(P<0.05).Compared with those in the model group,MSI and 5-HT,adrenaline,glucagon and blood glucose levels were decreased in the acupuncture PC6 group and traditional medicine group(P<0.05),while insulin level was not significantly changed(P>0.05).The adrenaline level in the traditional medicine group was lower than that in the acupuncture PC6 group(P<0.05).The acupuncture upper limbs group had lower MSI and higher insulin level than the model group(P<0.05),while there were no significant differences in the levels of 5-HT,adrenaline,glucagon or blood glucose between the two groups(P>0.05).Conclusion Both difenidol and acupuncture at PC6 can effectively relieve motion sickness.
