Preventive effect of Zusanli acupoint injection with dexamethasone on nausea and vomiting after gynecological laparoscopic surgery under general anesthesia
10.3969/j.issn.1009-0754.2024.03.017
- VernacularTitle:足三里穴位注射盐酸地塞米松对妇科腹腔镜手术全麻术后恶心呕吐的预防作用分析
- Author:
Xiaolan LIU
1
;
Yong ZHU
;
Mengting XU
;
Liping SHI
;
Chao PAN
;
Bo ZHANG
Author Information
1. 236600 安徽 太和,太和县人民医院麻醉科
- Keywords:
Laparoscopy;
Gynaecology;
Nausea;
Vomiting;
Dexamethasone;
TCM acupoints
- From:
Journal of Navy Medicine
2024;45(3):291-295
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the preventive effect of dexamethasone hydrochloride injection at Zusanli acupoint on nausea and vomiting after gynecological laparoscopic surgery under general anesthesia.Methods Between January 2021 and March 2022,78 patients scheduled for gynecological laparoscopic surgery were randomly divided into study group and control group with 39 cases in each group.Ondansetron(4 mg)was intravenously injected in both groups before surgery,and dexamethasone(5 mg)was injected additionally at Zusanli acupoint in the study group.The perioperative heart rate(HR),mean arterial pressure(MAP),blood oxygen saturation(SpO2)and operation time of the two groups were recorded.The levels of motilin and vasoactive intestinal peptide and the incidences of nausea,vomiting and routine adverse reactions were compared between the two groups.Results There was no significant difference in HR,MAP,SpO2 or operation time between the two groups before and 48 h after operation(P>0.05).The incidences of nausea and vomiting in the study group were lower than those in the control group 24 h after operation.Postoperative motilin and vasoactive intestinal peptide levels in the study group were lower than those in the control group(P<0.05).Postoperative motilin and vasoactive intestinal peptide levels in the control group were higher than those before operation(P<0.05).There was no significant difference in the total incidences of routine adverse reactions such as fatigue or headache between the two groups(P>0.05).Conclusion Dexamethasone hydrochloride injection at Zusanli acupoint is helpful to stabilize the motilin and vasoactive intestinal peptide levels and significantly reduce the incidences of postoperative nausea and vomiting.
