Bedside lung ultrasound B-line counting and peripheral blood eosinophil in diagnosing pneumonia in patients with chronic obstructive pulmonary disease and related factors
10.3969/j.issn.1009-0754.2023.12.007
- VernacularTitle:床旁肺超声B线计数及外周血嗜酸性粒细胞评估慢性阻塞性肺疾病并发肺炎的价值及其相关因素分析
- Author:
Mei SHI
1
;
Li'an ZHOU
;
Yeliu FU
Author Information
1. 570208 海南 海口,中南大学湘雅医学院附属海口医院超声医学科
- Keywords:
Bedside;
Lung ultrasound;
B-line counting;
Eosinophil;
Chronic obstructive pulmonary disease;
Pneumonia
- From:
Journal of Navy Medicine
2023;44(12):1243-1247
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the value of bedside lung ultrasound B-line counting and peripheral blood eosinophil(EOS)in diagnosing chronic obstructive pulmonary disease(COPD)complicated with pneumonia and related factors.Methods A total of 165 COPD patients diagnosed and treated in Affiliated Haikou Hospital of Xiangya School of Medicine of Central South University from August 2019 to August 2021 were enrolled.Of them,55 had pneumonia(pneumonia group)and 110 did not have pneumonia(non-pneumonia group).B-line counting and EOS percentage were compared between the 2 groups.Receiver operating characteristic(ROC)curve was drawn to analyze the area under curve(AUC),sensitivity and specificity of B-line counting and EOS percentage in diagnosing pneumonia in COPD patients.Binary logistic regression model was used to analyze the risk factors affecting COPD patients complicated with pneumonia.Results The B-line counting and the percentage of EOS in the pneumonia group were significantly higher than those in the non-pneumonia group(P<0.05).ROC curve analysis showed that the AUC values of B-line counting and EOS percentage for the diagnosis of pneumonia in COPD patients were 0.850 and 0.759,respectively(P<0.05);the sensitivities were 69.10%and 60.00%,and the specificities were 89.10%and 84.50%.There were significant differences in the antibiotic use time,basis diseases,mechanical ventilation time,glucocorticoid use time,and the incidence of multiple organ dysfunction syndrome(MODS)between the 2 groups(P<0.05).Binary logistic regression analysis showed that age≥60 years old,antibiotic use time>14 d,mechanical ventilation time≥10 d,glucocorticoid use time≥7 d,and MODS were independent risk factors affecting the development of pneumonia in COPD patients(P<0.05).Conclusion Bedside lung ultrasound B-line counting and peripheral blood EOS have high clinical value in diagnosing pneumonia in COPD patients.Age,antibiotic use time,basic diseases,mechanical ventilation time,glucocorticoid use time,and MODS may increase the risk of pneumonia in COPD patients.
