Value of lung function test parameters combined with CAT score in predicting acute attack in elderly patients with COPD
10.3969/j.issn.1009-0754.2023.12.005
- VernacularTitle:肺功能测试参数联合CAT评分对老年慢性阻塞性肺疾病患者急性发作的预测价值
- Author:
Minghao GU
1
;
Zhong GUO
;
Zihan CHENG
Author Information
1. 200233 上海,上海市第六人民医院徐汇院区呼吸内科
- Keywords:
Lung function;
Chronic obstructive pulmonary disease;
COPD assessment test;
COPD acute attack
- From:
Journal of Navy Medicine
2023;44(12):1232-1236
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the predictive value of lung function test parameters combined with assessment test(CAT)score of chronic obstructive pulmonary disease(COPD)for acute attack in elderly COPD patients.Methods A total of 150 elderly COPD patients admitted to Shanghai Sixth People's Hospital from June 2020 to December 2022 were retrospectively enrolled.According to the diagnostic criteria of acute attack of COPD,the patients were divided into acute attack group(n=45)and stable group(n=105).The clinical basic data,forced expiratory volume in 1 second(FEV1),forced vital capacity(FVC),forced expiratory volume in 3 seconds(FEV3),percentage of FEV1 to predicted value(FEV1%),FEV1/FVC and FEV1/FEV3 were compared between the 2 groups.Respiratory symptoms and COPD severity were assessed by St.George's respiratory questionnaire(SGRQ),modified British Medical Research Council respiratory questionnaire(mMRC),and CAT questionnaire.Correlation analysis and binary logistic regression analysis were used to determine independent risk factors for acute attack in elderly COPD patients.Receiver operator characteristic(ROC)curves were drawn to evaluate the independent and combined predictive value of risk factors.Results FEV1,FVC,FEV1%,FEV1/FVC,and FEV1/FEV3 in the acute attack group were significantly lower than those in the control group(P<0.05).The scores of SGRQ,mMRC and CAT in the acute attack group were significantly higher than those in the control group(P<0.05).Correlation analysis showed that FEV1,FVC,FEV1%,and FEV1/FVC were negatively correlated with acute attack of COPD,while mMRC and CAT scores were positively correlated with acute attack of COPD(P<0.05).Logistic regression analysis showed that the decrease of FEV1 and the increases of mMRC and CAT scores were the risk factors of acute attack of COPD in elderly patients.ROC analysis showed that FEV1 and CAT were of high value in independent prediction of acute attack of COPD in elderly patients.Conclusion Lung function test parameters and scores related to various respiratory symptoms in elderly patients with COPD will change significantly during acute attack.FEV1 and CAT are important independent risk factors and predictors of acute attack,which can be used for early monitoring,evaluation and prevention of acute attack in elderly patients with COPD in the future.
