Vacuum sealing drainage in treating limb burns combined with seawater immersion:an analysis of outcome
10.3969/j.issn.1009-0754.2023.12.002
- VernacularTitle:肢体烧伤合并海水浸泡后伤口负压封闭引流治疗效果分析
- Author:
Hongwei BAO
1
;
Li JIANG
;
Juan FAN
;
Anjing REN
Author Information
1. 200050 上海,海军军医大学附属第九〇五医院骨科
- Keywords:
Burn;
Seawater immersion;
Vacuum sealing drainage
- From:
Journal of Navy Medicine
2023;44(12):1218-1221
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the outcome of vacuum sealing drainage in treating limb burns combined with seawater immersion.Methods Sixteen healthy male New Zealand white rabbits were randomly divided into conventional debridement group(8 rabbits)and vacuum sealing drainage group(8 rabbits)after limb burns and seawater immersion.The wound healing was observed in the 2 groups,and the wound tissue was collected immediately,7 days,and 14 days after modeling for HE staining to observe the histopathological changs and for immunohistochemistry to detect the expression of Ki67 and CD31.Results The healing time was significantly shorter in the vacuum sealing drainage group than that in the conventional debridement group after limb burns and seawater immersion.The expression of Ki67 and CD31 in the vacuum sealing drainage group were significantly higher than that in the conventional debridement group.Conclusion Vacuum sealing drainage is more beneficial to wound healing than conventional debridement.
