Clinical value of blood hormone values coupled with ultrasonography in the prediction of the outcome of early vaginal bleeding in intrauterine pregnancy
10.3969/j.issn.1009-0754.2018.02.021
- VernacularTitle:血激素值联合B超检查预测宫内妊娠早期阴道流血结局的临床价值
- Author:
Xiaoning WANG
1
;
Li GENG
;
Jie DING
Author Information
1. 解放军第三医院妇产科
- Keywords:
Intrauterine pregnancy;
Early pregnancy;
Vaginal bleeding;
Pregnant outcome
- From:
Journal of Navy Medicine
2018;39(2):158-161
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical value of blood β-HCG, progesterone (P)and estradiol (E2) coupled with ultrasonography in the prediction of the outcome of early vaginal bleeding in intrauterine pregnancy .Methods One hundred and fifty patients who were hospitalized from February 2016 to February 2017 and diagnosed as threatened abortion due to vaginal bleeding were enrolled in the study .In accordance with the pregnancy outcome , the patients were divided into the abortion group ( n=64 ) and the continuing pregnancy group (n=87), and another 80 normal pregnant women were selected as the control group .On the day upon ad-mission, the patients received radioimmunoassay to detect blood β-HCG, P and E2, in addition to abdominal ultrasonography , and 48 hours later β-HCG level was reexamined .Results (1) The levels ofβ-HCG, P and E2 in the abortion group were all significantly low-er than those of the continuing pregnancy group and the normal group (P<0.01).But there was no statistical significance in the levels ofβ-HCG, P and E2 in the continuing pregnancy group as compared with those of the normal control group (P>0.05).(2) Abdomi-nal ultrasonography showed that in the abortion group only 21.88%(14/64) of the cases had embryo bud , of which 4 cases could be detected to have fetal heart beat at 7-8 week of pregnancy , but at week 12 missed abortion occurred .For those cases that were detected to have no fetal heart in the primary ultrasonography , fetal heart beat was detected 1-2 weeks later.For those cases with normal fetuses with ultrasonography at 11-13 weeks of pregnancy , they were advised to have medical follow-ups till late pregnancy .Conclusion Dy- namic monitoring should be made in the cases of early vaginal bleeding in intrauterine pregnancy .Detection results of β-HCG, P and E2 coupled with abdominal ultrasonography could be used for accurate evaluation of pregnant outcome .
