Effects of Jinsanzhen acupuncture combined with continuous aerobics on the rat model with chronic stress-induced depression
10.3969/j.issn.1009-0754.2018.02.012
- VernacularTitle:"靳三针"结合持续有氧运动对慢性应激 抑郁模型大鼠的干预作用
- Author:
Jingxian JIANG
1
;
Dagui CHEN
;
Jie LUAN
;
Weihong LIU
;
Jiachun WANG
Author Information
1. 江苏省常州市食品药品监督检验中心
- Keywords:
Jinsanzhen acupuncture;
Aerobic exercise;
Behavior;
Rat
- From:
Journal of Navy Medicine
2018;39(2):125-128
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the therapeutic effects of Jinsanzhen acupuncture combined with continuous aerobics on the rats with chronic stress-induced depression .Methods The chronic stress-induced depression rat model was developed by using chronic unpredicted mild stimulation ( CUMS) .Thirty male SD rats were randomly divided into the normal control group , the model group ( or the experimental group ) and the treatment group .The rats in the normal control group were given normal feed , but the rats of the model group received stimulation every morning , and the rats of the treatment group also received stimulation every morning , except that they were placed on the treadmill for 30-minute running exercise every afternoon , and then, they were treated with Jinsanzhen acupuncture . Four weeks later , various indicators were detected in the rats of all the groups .Results As compared with that of the rats in the model group, the platform-jumping latency of the rats in the Jinsanzhen therapy combined with continuous aerobics group was elevated , and the number of errors was decreased (P<0.05), open field horizontal and vertical scores were all increased to certain extents (P<0.05), the latency of water maze was decreased and the number of passing through the platform were increased (P<0.05).Pathologic, elec-tron microscopic and Nissl detection results indicated that Jinsanzhen acupuncture combined with continuous aerobics could produce cer -tain effects on the brain tissue of the model group .Conclusion Jinsanzhen acupuncture combined with continuous aerobic exercise could produce good effects on the rats with chronic stress-induced depression .
