Research on the risk factors related with clinicopathology in canceration of colorectal laterally spreading tumors
10.3969/j.issn.1009-0754.2018.02.011
- VernacularTitle:大肠侧向发育型肿瘤癌变的临床病理相关风险因素研究
- Author:
Liangliang ZHU
1
;
Yongqi SHAN
;
Feihu YAN
;
Zhen WANG
;
Enda YU
Author Information
1. 海军军医大学附属长海医院肛肠外科
- Keywords:
Laterally spreading tumor;
Colorectal cancer;
Caneration;
Risk factor
- From:
Journal of Navy Medicine
2018;39(2):121-124
- CountryChina
- Language:Chinese
-
Abstract:
Objective To identify clinicopathological features of laterally spreading tumors (LST) and explore the cancera-tion risk factors related with LSTs .Methods A retrospective analysis of clinical and pathological data was made in the patients , who underwent colonoscopy from May 2011 to May 2017 in the Digestive Endoscopy Center of Changhai Hospital and were conformed to the diagnostic criteria of LST and protruded-type adenoma ( PA) .Clinical features and related canceration risk factors of LST and its sub-type were analyzed and compared with those of PA .Results In the LST group, there were 422 patients, with a total of 439 LST le-sions, and in the PA group, there were 432 patients with 465 lesions.Canceration rates of the LST-G group, the LST-NG group and the PA group were respectively 7.72%, 11.69%and 2.58%.Regression analysis indicated that the canceration risk factors of LST were associated with those of PA , and morphological classification , pathogenic sites and polyp size were related canceration risk factors in LST.Morphological typing was LST-NG and pathogenic site was located at the left half colon , and the larger its size , the greater the canceration risk.Patient age, pathogenic site and polyp size were 3 canceration related risk factors of PA .Old age, pathogenic location at the right half colon and larger polyp size were high canceration risk factors .Conclusion LST seems to have greater malignant poten-tial than PA, especially the LST-NG type.The canceration risk factors of LST and PA are obviously different , indicating that the can-ceration mechanism of LST and PA might be entirely different .
