Clinical observation on the effects of low molecular weight heparin combined with ginkgo dipyridamole on the patients with acute cardiogenic cerebral embolism
10.3969/j.issn.1009-0754.2017.01.019
- VernacularTitle:低分子肝素钙联合银杏达莫治疗急性心源性脑栓塞患者临床疗效观察
- Author:
Changming GENG
1
;
Daomin WEI
;
Jie WEI
;
Xiao KONG
Author Information
1. 解放军第八五医院神经内科
- Keywords:
Acute cardiogenic;
Cerebral embolism;
Low molecular weight heparin;
Ginkgo dipyridamole
- From:
Journal of Navy Medicine
2017;38(1):57-59
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical efficacy of low molecular weight heparin combined with ginkgo dipyridamole on the patients with acute cardiogenic cerebral embolism .Methods Eighty cases of cardiogenic cerebral embolism admitted into the Department of Neurology of the hospital from July 2015 to July 2016 were recruited as research subjects .With the knowledge of the pa-tients and consent of their dependents , the patients were equally divided into 2 groups: the observation group and the control group , each consisting of 40 patients.After admission into the hospital , the patients of the 2 groups were given the same basic treatment and the treatment for complication prevention .The patients of the observation group received treatment of low molecular weight heparin com -bined with ginkgo dipyridamole for the treatment of acute cardiogenic cerebral embolism , while the patients of the control group were just given low molecular weight heparin .Recovery of neurological insufficiency and clinical efficacy were compared between the 2 groups both before and after treatment , and at the same time, adverse reactions were also observed and compared between the 2 groups.Results After treatment, the neurological function scores of the observation group were significantly higher than those of the control group , and statistical significance could be seen when comparisons were made between them (P<0.05).Total therapeutic efficacy of the observa-tion group was 97.5%, which was significantly higher than that of the control group (67.5%), also with statistical significance (P<0.05).There was no statistical significance in adverse reactions , when comparisons were made between the 2 groups(P>0.05). Conclusion Low molecular weight heparin combined with ginkgo dipyridamole in the treatment of acute cardiogenic cerebral embolism could produce much better effect than single application of low molecular weight heparin .
