Levels of cytokine and 25-hydroxyvitamin D in the blood of infants with rotavirus enteritis

VernacularTitle:轮状病毒肠炎婴幼儿血清细胞因子与血清25-羟维生素D水平的研究
Author: Wei HUANG ¹ ; Ying SU ; Jianying SHAO ; Li SUN ; Mingyue XIA ; Mingli LI
Author Information

1. 秦皇岛市第一医院
Keywords: Rotavirus enteritis; Cytokine; 25-hydroxyvitamin D; Infant
From: Journal of Navy Medicine 2016;37(4):339-340
CountryChina
Language:Chinese
Abstract: Objective To explore levels of cytokine and 25-hydroxyvitamin D in the blood of infants with rotavirus enteritis and their clinical significance.Methods Sixty-eight infants with rotavirus enteritis were recruited as the research group, while 56 healthy infants who underwent normal physical checks were assigned as the control group.Fasting venous blood samples were collected for the detection of cytokine and 25-hydroxyvitamin D levels by RP-HPLC method.Results The levels of IL-2, IL-6, TNF-αin the in-fants of the research group were significantly higher than those of the infants of the control group (P<0.01).The level of 25-hydroxyvi-tamin D of the study group was obviously lower than that of the control group (P<0.05).Conclusion The elevated levels of IL-2, IL-6, TNF-αin the infants with rotavirus enteritis were associated with the decreased level of 25-hydroxyvitamin D.