Medical treatment and pharmaceutical care of the patient with hyperthyroidism coupled with cholestatic liver injury
10.3969/j.issn.1009-0754.2016.02.011
- VernacularTitle:甲状腺功能亢进合并胆汁瘀积性肝损伤患者的治疗与药学监护
- Author:
Li GONG
1
;
Wansheng CHEN
;
Xia TAO
;
Liping TU
;
Wenhui HUANG
;
Xingyun HOU
Author Information
1. 200003 上海，上海长征医院药材科; 解放军第四一一医院
- Keywords:
Hyperthyroidism;
Cholestatic liver injury;
Methimazole;
Steroid;
Pharmaceutical care
- From:
Journal of Navy Medicine
2016;37(2):129-133
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore methods for the provision of medical treatment and pharmaceutical care of the patients with hyperthyroidism coupled with cholestatic liver injury.Methods The clinical pharmacist was involved in the whole treatment course of one patient with hyperthyroidism and cholestatic liver injury.The pharmacist focused on the monitoring of the use of steroids and hepato-protective drug, established good communication with the physician, and suggestions were made as to the adjustment of therapeutic drugs, so that adverse drug reactions could be minimized.At the same time, medication education was given to the patient, so as to en-sure the safety and efficacy of medication.Results Total bilirubin of the patient was decreased from 574 μmol/L to 113 μmol/L and the state of the illness was alleviated, and as a consequence, the compliance in drug use was raised too.Conclusion The medical per-sonnel should be highly aware of the probability that cholestasis could be worsened by the medication of thionamide, and clinical phar-macists should pay great attention to the monitoring of the liver function and the medication of steroids.
