Clinical research on the changes of hemorheology in H type hypertension patients
10.3969/j.issn.1009-0754.2015.06.015
- VernacularTitle:H 型高血压患者血液流变学的临床研究
- Author:
Hui DONG
1
;
Jingtao TONG
;
Xiaoqin SHAO
Author Information
1. 海军东海舰队机关医院
- Keywords:
H type hypertension;
Homocysteine;
Hemorheology
- From:
Journal of Navy Medicine
2015;(6):514-516
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore changes of hemorheology in H type hypertension patients and its clinical significance . Methods One hundred and twenty-four primary hypertension patients were chosen for the study , and were divided into the H type hyper-tension group (n=62) and the control group (n=62) in accordance with the levels of serum homocysteine .Mean levels of 24-h dynamic blood pressure , whole blood viscosity , plasma viscosity , hematocrit and fibrinogen were detected and analyzed respectively .Results No significant differences could be found in 24-h dynamic systolic and diastolic blood pressures , and there was no statistical significance , when comparisons were made between the 2 groups(P>0.05).Whole blood viscosity, plasma viscosity, hematocrit, fibrinogen in the H type hypertension group [(15.38 ±1.03)mPa? s、(5.91 ±0.32)mPa? s、(2.65 ±0.83)mPa? s、(52.96 ±2.11)%、(5.52 ±0.93) g/L] were significantly higher than those of the control group [(11.35 ±1.24)mPa? s]、(5.36 ±1.52)mPa? s、(1.52 ±1.04)mPa? s、(50.00 ±1.03)%、(4.03 ±1.33)g/L](P<0.05).Whole blood viscosity, plasma viscosity, hematocrit, fibrinogen in the grade 3 H type hypertension patients were significantly higher than those of the grade 1 and grade 2 H type hypertension patients(P<0.05), while whole blood viscosity and fibrinogen in grade 2 H type hypertension patients were higher than those of the grade 1 H type hypertension patients (P<0.05).Conclusion Significant elevation of blood viscosity in the H type hypertension patients might be closely associated with the oc-currence of cardio-cerebraovascular events and efforts should be made for positive intervention .
