Meta-analysis of randomized controlled trail research literature of traditional Chinese medicine for cancer telated fatigue
10.3969/j.issn.1009-0754.2015.04.008
- VernacularTitle:补气中药治疗癌性疲劳随机对照临床研究文献 Meta 分析
- Author:
Qi ZHU
1
;
Wenfu TANG
;
Ying ZHANG
Author Information
1. 四川大学华西医院
- Keywords:
Cancer related fatigue;
traditional Chinese medicine;
randomized controlled trail;
Meta-anlysis
- From:
Journal of Navy Medicine
2015;(4):302-307
- CountryChina
- Language:Chinese
-
Abstract:
Objective According meta-anlysis to asses tonic medicine in the treatment of cancer related fatigue(CRF).To provide the scientific basis for Chinese medicine treatment of CRF.Methods “cancer related fatigue”,“Chinese herb”,“traditional Chinese medicine”,“botanicals”,“complementary medicine”,“palliative medicine”as keywords,We searched PubMed,the Co-chrane library,Cnki,Vip,Wanfang med online,Chinese biomedical literature on disc(CBM)of relevant randomized controlled trail (RCT)literature in 1994 -2014.The quality of RCT was assessed according to “the cochrane collaboration′s tool for assessing risk of bias”,which recommended by the cochrane library.Meta-anlysis were conducted with the cochrane collaboration′s RevMan 5.3.Results A total of nineteen literatures,involving 1904 patients with CRF.The results of meta-analysis showed that the experimental group and the control group have significant differences in the effective rate[RR =1.72,95%CI(1.55,1.92)],Brief fatigue inventory[RR =1.92,95%CI(1.61,2.29)],Traditional-Chinese-medicine-symtom-score system[RR =1.59,95%CI(1.27,1.99)](P <0.05). Conclusion The evidence currently available indicates that Tonic medicine had a statistically significant Improve traditional Chinese medicine symtom and the quality of life of patients with CRF.But further large scale,high quality RCTs are needed.
