Clinical observation on the effect of intensive early fluid resuscitation in 30 cases of severe acute pancreatitis
10.3969/j.issn.1009-0754.2015.02.015
- VernacularTitle:重症急性胰腺炎早期强化液体复苏治疗30例临床观察
- Author:
Xiaohong ZENG
1
;
Changyun LIU
;
Li ZHANG
;
Jiao LÜ
;
Yunxing SHI
;
Yongping LI
;
Pingping QIAN
Author Information
1. 解放军第四一一医院消化内科
- Keywords:
Severe acute pancreatitis ( SAP);
Acute reaction stage;
Fluid resuscitation
- From:
Journal of Navy Medicine
2015;(2):140-142
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the treatment method and effect of intensive early fluid resuscitation on the patients with severe acute pancreatitis ( SAP) in acute reaction stage .Methods Fifty-eight patients with SAP treated in the hospital from Aug .2008 to Mar.2010 were randomly divided into the treatment group (n=30) and the control group (n=28).The patients in the former group were given intensive early fluid resuscitation , either with hydroxyethylstarch and an increased amount of colloidal fluid or occasionally with a certain amount of plasma and albumin .Physiological saline and/or balanced salt solution were used as crystal fluid , with a ratio of 1∶2-1∶1.The patients in the latter group were supplemented or treated with an effective circulating blood volume and electrolyte im -balance correction .They were daily infused with a certain amount of plasma and albumin .Analyses were made on such reactions as re-spiratory failure , renal insufficiency and cardiac dysfunction in the acute reaction stage in patients with SAP .Results With regard to the incidence of complications during the acute reaction stage for the patients of the 2 groups, the incidence of respiratory failure , renal insufficiency and cardiac dysfunction in the patients of the treatment group was significantly lower than that in the patients of the control group, with statistical significance(P<0.05).With regard to the amount of daily fluid infusion for the groups during the acute reaction stage, the amount of infusion for the treatment group was significantly lower than that for the control group , with statistical significance (P<0.05).Conclusion Effective and active early fluid resuscitation during the acute reaction stage in SAP patients could decrease the incidence of complications .The supplementation of Hydroxyethylstarch and the increase in the ratio of colloidal fluid could produce better resuscitative effects on patients with SAP .
