Application of narrow-band imaging cystoscopy in the diagnosis of interstitial cystitis
10.3969/j.issn.1009-0754.2015.02.011
- VernacularTitle:窄带成像膀胱镜诊断间质性膀胱炎的应用
- Author:
Yun OUYANG
1
;
Cuilong LIU
;
Weimin GUAN
;
Yubo ZHAO
;
Xuesong GAO
;
Yiguang WU
;
Yansheng XU
Author Information
1. 海军总医院泌尿外科
- Keywords:
Narrow-band imaging;
Cystoscopy;
Cystalgia;
Interstitial cystitis;
Diagnosis
- From:
Journal of Navy Medicine
2015;(2):128-130,133
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the value of narrow-band imaging (NBI) cystoscopy in the diagnosis of interstitial cysti-tis (IC).Methods From Sep.2009 to Mar.2014, 65 patients highly suspected of having IC were included in the study .First, con-ventional white-light imaging(WLI)cystoscopy was performed under spinal anesthesia by a senior urologist .Then, NBI cystoscopy was conducted independently by a junior urologist .Following hydro-distention test , the above two urologists made conventional observation by WLI cystoscopy , and biopsy was performed to see if abnormal bladder mucosa could be detected .Results Conventional WLI cysto-scopy before hydrodistention revealed that 5 patients out of 65 had ulcerative pathological lesion and 23 patients had non-ulcerative capil-lary-rich area .When NBI cystoscopy was administered , 28 WLI-positive cases were detected , and another 31 WLI-negative cases were found to have non-ulcerative capillary-rich area.WLI cystoscopy after hydrodistention revealed that 5 cases with ulcerative lesion had mucosa rupture with bleeding at the site of ulcer , and all the 54 cases with non-ulcerative capillary-rich area under NBI cystoscopy and 2 NBI-negative cases were found to have petechial hemorrhage and glomerulus -like erythema.Biopsies performed in 61 cases with ab-normal bladder mucosa revealed that 59 cases had chronic inflammation and 2 cases were diagnosed to be carcinoma in situ .Thus, 59 were confirmed to be IC cases.In the diagnosis of IC under the WLI mode before hydrodistention , the sensitivity, specificity and Kappa values were 44.1%, 66.7% and 0.032 respectively, while under NBI mode, the sensitivity, specificity and Kappa values were 96.6%, 66.7%and 0.633 respectively.Conclusion Compared with WLI cystoscopy, NBI cystoscopy seemed to be more sensitive in the diagnosis of IC before hydrodistention .The NBI-positive area was highly identical to the positive area after hydrodistention .It had good application value in IC diagnosis .
