Safety and efficacy of oral lactulose coupled with bifico as pre-surgical bowel preparation in patients with primary liver cancer
10.3969/j.issn.1009-0754.2015.01.013
- VernacularTitle:乳果糖联合培菲康用于原发性肝癌患者术前肠道准备的安全性与有效性探讨
- Author:
Jieqiong ZHAO
1
;
Hongling WANG
;
Jing XU
;
Xueqing SHAO
Author Information
1. 第二军医大学附属东方肝胆外科医院肝外一科
- Keywords:
Lactulose;
Bifico;
Liver tumor;
Bowel preparation
- From:
Journal of Navy Medicine
2015;(1):34-36
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the safety and efficacy of oral lactulose coupled with bifico as pre-surgical bowel preparation in patients with primary liver cancer .Methods With the knowledge and consent of the patients , a total of 80 patients were randomly divided into 2 groups, the experimental group and the control group , each consisting of 40 patients.The experimental group received o-ral lactulose plus bifico and the control group was given oral polyethylene glycol electrolytes as pre -surgical bowel preparation before sur-gery.Then, patients′tolerance, acceptance, adverse reactions, bowel cleansing and post-surgical bowel movement recovery were ob-served and compared between the 2 groups.Results No statistical significance in bowel cleansing could be observed , following imple-mentation of the drugs for the two groups (P>0.05).The texture and acceptance of the drugs for the experimental group were obviously superior to those of the control group, with statistical significance(P<0.05).With the exception of allergic reaction, no statistical difference could be noted in adverse reactions to pre-surgical bowel preparation for both groups (P>0.05).The incidence of other ad-verse reactions for the experimental group was lower than that of the control group , with statistical significance(P<0.05).Following pre-surgical bowel preparation , frequency of defecation and recovery of liver function for the experimental group were superior than those of the control group, also with statistical significance, when comparisons were made between the 2 groups (P<0.05).Conclusion Lactulose coupled with bifico as pre-surgical bowel preparation was safe and feasible , which could not only improve the sense of comfort for the patients, but increased their compliance , and decreased medical cost as well .
