Protective effects of Qijia oral liquid on hematopoiesis in irradiated mice
10.3969/j.issn.1009-0754.2015.01.006
- VernacularTitle:芪加口服液对辐射损伤小鼠造血功能的保护作用
- Author:
Ying TANG
1
;
Qingmin WANG
;
Lina LIU
;
Wenbin CHEN
Author Information
1. 海军医学研究所
- Keywords:
Qijia oral liquid;
Mouse;
Radiation injury;
Hematopoietic system
- From:
Journal of Navy Medicine
2015;(1):13-15
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the protective effect of Qijia oral liquid on hematopoiesis in mice with radiation injury . Methods Fifty mice were randomly divided into the control group , the model group, the low, moderate and high dosage of Qijia oral liquid groups (100, 200, 400 mg/kg).The animals were irradiated with 60Co gamma ray with an absorbed dosage of 6.0 Gy.The number of white blood cells , spleen index , the number of endogenous spleen nodules , bone marrow nucleated cells and DNA content were measured and analyzed .Results Nine days after gamma ray exposure , the number of nucleated cells , DNA content, the number of white blood cells , spleen nodules and spleen index in all the drug groups were increased significantly , as compared with those of the model group (P<0.01 or P<0.05).Conclusion Qijia oral liquid presented a protective effect on the hematopoietic system in mice with radiation injury .
