Clinical Experience of Lin Lizhu in Applying the Method of Strengthening Spleen and Soothing Liver to Intervene Patients with Primary Liver Cancer After TACE
10.13359/j.cnki.gzxbtcm.2025.11.031
- VernacularTitle:林丽珠运用健脾疏肝法干预原发性肝癌TACE术后患者的临床经验
- Author:
Shang XIANG
1
;
Hanhan LI
;
Wei GUO
;
Ling YU
;
Hanrui CHEN
Author Information
1. 广州中医药大学,广东 广州 510405
- Keywords:
primary liver cancer(PCL);
transarterial chemoembolization(TACE);
strengthening spleen and soothing liver;
invigorating spleen and stomach;
soothing liver and nourishing blood;
detoxifying and dispersing stasis;
Sini Kang'ai Formula;
tumor recurrence;
postop
- From:
Journal of Guangzhou University of Traditional Chinese Medicine
2025;42(11):2845-2851
- CountryChina
- Language:Chinese
-
Abstract:
As an adjuvant therapy,transarterial chemoembolization(TACE)can prolong the disease-free survival and overall survival of patients with primary liver cancer(PCL).However,postoperative adverse reactions and recurrence still possibly persist.Based on years of clinical practice,Professor Lin Lizhu proposes that patients with PCL undergoing TACE exhibit pathological mechanisms characterized by deficiency,stagnation,toxicity,and stasis.In clinical practice,these patients can be treated with Chinese herbal medicine based on the therapeutic principle of strengthening spleen and soothing liver.The treatment strategy involves:invigorating spleen and stomach to restore healthy qi,soothing liver and nourishing blood to support liver function,and detoxifying and dispersing stasis to prevent recurrence.Derived from the classic formula Sini San,Professor Lin has developed Sini Kang'ai Formula,which mainly consists of Eupolyphaga Steleophaga,Bupleuri Radix,Paeoniae Radix Alba,Aurantii Fructus Immaturus,Glycyrrhizae Radix et Rhizoma,Codonopsis Radix,Persicae Semen,Cremastrae Pseudobulbus Pleiones Pseudobulbus,etc.In clinical application,Sini Kang'ai Formula should be flexibly modified depending on the characteristic symptom patterns of patients during the perioperative period of TACE,thus to alleviate postoperative adverse reactions,prevent tumor recurrence,prolong disease-free survival and overall survival,and improve patients' quality of life.
