Study on the Characteristics of Traditional Chinese Medicine Syndrome Elements and Distribution Patterns of Syndrome Types in Senile Osteoporosis
10.13359/j.cnki.gzxbtcm.2025.11.009
- VernacularTitle:老年性骨质疏松症中医证素特征及证型分布规律研究
- Author:
Guopeng HU
1
;
Feng QIU
;
Chao LI
;
Feng LI
;
Hongwen GAO
Author Information
1. 无锡市惠山区中医医院,江苏无锡 214177
- Keywords:
senile osteoporosis;
TCM syndrome elements;
TCM syndrome patterns;
spleen-kidney yang deficiency;
liver blood deficiency;
kidney essence insufficiency;
qi stagnation and blood stasis
- From:
Journal of Guangzhou University of Traditional Chinese Medicine
2025;42(11):2683-2688
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the characteristics of traditional Chinese medicine(TCM)syndrome elements and the distribution patterns of TCM syndromes in senile osteoporosis(SOP),providing a reference for TCM treatment of SOP.Methods A cross-sectional study was conducted on 200 SOP patients aged over 70 years treated at Wuxi Huishan Chinese Medicine Hospital from January 2022 to June 2023.General information and TCM diagnostic data were collected.The syndrome element differentiation scoring method was employed for analysis.Results(1)Among the 200 SOP patients,the most prevalent disease-location syndrome element was kidney(61.50%),followed by liver(48.50%),bones and tendons(45.50%),spleen(37.00%),meridians(25.50%),heart(12.50%),and lung(10.50%).Statistical analysis showed significantly higher syndrome element scores for kidney,liver,bones and tendons,spleen,and meridians compared to heart and lung(P<0.01).(2)Regarding disease-nature syndrome elements,deficiency-type elements predominated,with yang deficiency(52.50%)being most common,followed by blood deficiency(46.00%),essence depletion(45.50%),qi deficiency(45.50%),yin deficiency(37.00%),unconsolidation(25.50%),and qi sinking(15.50%).Yang deficiency,blood deficiency,essence depletion,qi deficiency,and yin deficiency scores were significantly higher than those of insecurity and qi sinking,the difference being statistically significant(P<0.01).Among excess-type elements,cold(47.00%)was most prevalent,followed by blood stasis(45.00%),qi stagnation(43.50%),dampness(34.50%),phlegm(27.50%),and heat(25.00%).Cold and blood stasis scores were significantly higher than phlegm,while cold,blood stasis,qi stagnation,dampness,and phlegm scores were significantly higher than heat,the difference being statistically significant(P<0.05).(3)Eighteen TCM syndrome patterns were identified.Spleen-kidney yang deficiency(40.00%)was most frequent,followed by liver blood deficiency(37.50%),kidney essence insufficiency(35.00%),qi stagnation and blood stasis(31.00%),cold congelation and obstruction(25.50%),phlegm-damp obstruction(27.50%),and qi-yin deficiency with qi insecurity(11.00%).Based on syndrome element scores,the primary syndromes were defiined as spleen-kidney yang deficiency(35.60%),liver blood deficiency(25.13%),kidney essence insufficiency(18.32%),and qi stagnation and blood stasis(13.09%),etc.Conclusion The characteristic TCM syndrome elements of SOP patients involve qi-blood-yin-yang deficiency of kidney,spleen,and liver,combined with cold congelation,blood stasis,and qi stagnation.The main TCM syndromes are spleen-kidney yang deficiency,liver blood deficiency,kidney essence insufficiency,and qi stagnation with blood stasis.