Study on the Correlation Between Venous Thromboembolism and Traditional Chinese Medicine Constitution Types in Elderly Frail Patients
10.13359/j.cnki.gzxbtcm.2025.11.008
- VernacularTitle:老年衰弱患者静脉血栓栓塞症与中医体质类型的相关性
- Author:
Yan ZHOU
1
;
Yunyu LIANG
;
Jianfeng ZHUO
;
Xinmei LI
;
Xiaozhong LIN
Author Information
1. 广州中医药大学第二附属医院(广东省中医院)大学城医院综合二科,广东 广州 510120
- Keywords:
elderly frailty;
venous thromboembolism;
TCM constitution;
damp-heat constitution;
blood-stasis constitution;
qi-depression constitution;
risk factors;
Padua score;
Wells score
- From:
Journal of Guangzhou University of Traditional Chinese Medicine
2025;42(11):2677-2682
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the correlation between venous thromboembolism(VTE)and traditional Chinese medicine(TCM)constitution types in elderly frail patients.Methods A retrospective study was conducted on 1 428 elderly frail patients admitted to the Second Comprehensive Department of Guangdong Provincial Hospital of Chinese Medicine from January 2019 to June 2023.Patients were divided into a venous thrombsis(VT)group(n=187)and a non-VT group(n=1 241)based on VTE occurrence.Baseline data,including age distribution,Padua scores,Wells scores,and TCM constitution types,were compared between the two groups.Multivariate logistic regression analysis was performed to identify factors for influencing VTE in elderly frail patients.Results(1)Compared with the non-VT group,the VT group had significantly higher total hospitalization costs,length of stay,age,Fried scores,Padua scores,and Wells scores,with statistically significance(P＜0.001).(2)Compared with the non-VT group,the VT group had a higher proportion of high VTE-risk individuals and those with Wells scores of 2 points,with statistically significance(P＜0.001).(3)The age distribution of VTE patients showed an increasing trend in the age groups of 60-69,70-79,80-89,and ≥90-year-old,with a significant difference compared to the non-VT group(P＜0.001).(4)The VT group had a higher proportion of qi-deficiency,blood-stasis,and qi-depression constitutions than the non-VT group(P＜0.05 or P＜0.001).(5)Multivariate logistic regression analysis(after adjusting age,gender,frailty,and other scores)showed that qi-deficiency and yang-deficiency constitutions were non-susceptible,while damp-heat,blood-stasis,and qi-depression constitutions were susceptible to VTE in elderly frail patients(P＜0.05 or P＜0.01).Conclusion VTE in elderly frail patients is significantly correlated with TCM constitution types.Deviated constitutions are characteristic of TCM constitution types in elderly frail patients,and damp-heat,blood-stasis,and qi-depression constitutions are risk factors for VTE in this population.
