Development of Core Outcome Set for Clinical Research on Vitiligo Treated with Uyghur Medicine
10.13359/j.cnki.gzxbtcm.2025.10.034
- VernacularTitle:维吾尔医治疗白癜风临床研究核心结局指标集的构建
- Author:
Qian HUANG
1
;
Xinfeng GUO
;
Lihong YANG
;
Genghang CHEN
;
Wufuer TUERSON
;
Yiming Maimaiti TURSUNTAI
;
Abuduwayiti JULAITI
;
Zhijian LI
;
Shaonan LIU
Author Information
1. 广州中医药大学第二附属医院/广东省中医院,广东 广州 510120
- Keywords:
progressive vitiligo;
Uyghur medicine;
minority medicine;
clinical assessment;
core outcome set
- From:
Journal of Guangzhou University of Traditional Chinese Medicine
2025;42(10):2595-2602
- CountryChina
- Language:Chinese
-
Abstract:
Objective To develop a core outcome set(COS)for treatment of progressive vitiligo in Uyghur medicine,and to standardize the selection and reporting of outcome measures in relevant studies.Methods Based on the existing core outcome domain set of randomized controlled trials for vitiligo,additional outcome indicators reflecting the advantages and characteristics of Uyghur medical treatment were developed.Specific indicators for Uyghur medical treatment of progressive vitiligo were collected through literature review and semi-structured questionnaire surveys,and then a list of indicators were formed.The Delphi survey and consensus meetings were used to select core indicators.Results A total of 54 studies were included,and 86 questionnaires were collected.Through literature review and questionnaire surveys,a list of 28 indicators were obtained.After two rounds of Delphi survey and one consensus meeting,12 outcome indicators in 7 domains were finally determined,including vitiligo lesion area,repigmentation,disease control time,maintenance of repigmentation,recurrence rate,immune indicators,psychological health,patients' quality of life,adverse events,adverse reaction incidence,liver and kidney function monitoring,and Uyghur medicine syndrome differentiation of mucus.Additionally,some measurement tools for certain indicators were recommended.Conclusion The development of the COS for vitiligo treatment in Uyghur medicine helps to comprehensively evaluate the efficacy of Uyghur medicine,and will provide a model for establishing efficacy evaluation methods that conform to the characteristics of ethnic minority medicine.
