Exploring the Differentiation and Treatment Strategies for Hypokalemic Periodic Paralysis from the Perspective of Spleen-Kidney Correlation
10.13359/j.cnki.gzxbtcm.2025.10.033
- VernacularTitle:从脾肾相关探讨低钾性周期性麻痹的辨治思路
- Author:
Yingqi SHAN
1
;
Qingyang LIU
;
Tianshu GAO
Author Information
1. 辽宁中医药大学,辽宁沈阳 110032
- Keywords:
spleen-kidney correlation;
hypokalemic periodic paralysis(HypoPP);
spleen failing in transportation;
kidney failing in storage;
potassium imbalance;
strengthening the middle energizer;
reinforcing kidney essence;
Buzhong Yiqi Decoction;
Da Buyin Pills
- From:
Journal of Guangzhou University of Traditional Chinese Medicine
2025;42(10):2589-2595
- CountryChina
- Language:Chinese
-
Abstract:
Hypokalemic periodic paralysis(HypoPP)is a very rare but potentially life-threatening condition,often attacking suddenly,usually triggered by overeating or vigorous exercise,which complicates disease prevention and treatment and significantly lowers patients' quality of life.With the deepening of modern traditional Chinese medicine(TCM)research on the spleen's role in water metabolism and the kidney's function in storage,and with the achievements in western medicine's microscopic understanding of the disease,it has been found that TCM can utilize the micro-level physiological and pathological insights of modern medicine to elucidate the pathogenesis of diseases,thereby facilitating the establishment of a TCM management model for high-risk factors of diseases.This article explored the relationship between potassium balance and HypoPP from the perspective of spleen-kidney correlation.It is proposed that spleen failing in transportation and kidney failing in storing essence may lead to potassium imbalance,which constitutes a key pathogenesis of HypoPP.Prevention and treatment should focus on strengthening the middle energizer and simultaneously reinforcing kidney essence.Clinically,modified Buzhong Yiqi Decoction plus Da Buyin Pills has shown favorable therapeutic effects.The approach of making diagnosis and treatment of HypoPP based on potassium balance and from the perspective of spleen-kidney correlation may provide novel insights for its TCM prevention and management.
