Exploring the Onset Patterns of Epilepsy in 8 389 Patients Based on the Theory of Five Circuits and Six Qi
10.13359/j.cnki.gzxbtcm.2025.09.004
- VernacularTitle:基于五运六气理论探讨8 389例癫痫患者发病规律
- Author:
Yiqian ZHOU
1
;
Xinmeng YAO
;
Hao LIN
;
Zhengfu LI
;
Tianxing ZHANG
;
Cenglin XU
;
Zhong CHEN
;
Yingying MAO
Author Information
1. 浙江中医药大学第一临床医学院,浙江 杭州 310053
- Keywords:
five circuits and six qi;
epilepsy;
onset patterns;
TCM theory of five circuits and six qi;
wood circuit years;
wind manifestation years;
cold-damp years;
midsummer periods;
trigger factors
- From:
Journal of Guangzhou University of Traditional Chinese Medicine
2025;42(9):2114-2119
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the characteristics of epilepsy onset based on the theory of five circuits and six qi in traditional Chinese medicine(TCM).Methods A total of 8 389 epilepsy patients from a community-based natural population cohort study from UK Biobank were included.Frequency and constituent ratio analyses were performed to describe the distribution of epilepsy onset in relation to the five circuits and six qi elements,and statistical inferences were made using chi-square tests.Results The analysis revealed statistically significant differences existed in epilepsy onset across different heavenly stems,earthly branches,recombinant yearly circuit,celestial control and terrestrial effect,and dominant qi(all P＜0.05).From the perspective of circuits,the highest incidence occurred in years corresponding to the"Ji"and"Hai"years,while the lowest incidence was observed in"Bing"and"Mao"years.Years dominated by wood circuit and wind manifestations exhibited the highest incidence,whereas years with cold manifestations showed the lowest incidence,suggesting the liver as the primary pathological site in epilepsy.From the perspective of qi,the third dominant qi was most frequently associated with onset.Regarding presiding and subordinate qi,years with taiyin damp earth presiding and taiyang cold water subordinate had the highest incidence,while years with yangming dry metal presiding and shaoyang monarch fire subordinate had the lowest incidence,indicating that cold-damp years and midsummer periods are potential triggers for epilepsy.Conclusion There is a certain regularity in the epilepsy onset correlated with the features of five circuits and six qi,which can guide prevention and clinical diagnosis and treatment of epilepsy.
