Research Progress on Buyang Huanwu Decoction in the Treatment of Peripheral Neuropathic Pain
10.13359/j.cnki.gzxbtcm.2025.06.036
- VernacularTitle:补阳还五汤治疗周围神经病理性疼痛的研究进展
- Author:
Zijia CHEN
1
;
Kaihao CHEN
;
Dongmei WANG
Author Information
1. 南方医科大学中医药学院,广东 广州 510515;南方医科大学皮肤病医院,广东 广州 510091
- Keywords:
Buyang Huanwu Decoction;
peripheral neuropathic pain(PNP);
postherpetic neuralgia;
painful diabetic peripheral neuropathy;
trigeminal neuralgia;
painful radiculopathy;
review
- From:
Journal of Guangzhou University of Traditional Chinese Medicine
2025;42(6):1538-1544
- CountryChina
- Language:Chinese
-
Abstract:
Peripheral neuropathic pain(PNP)is a chronic pain condition caused by the primary damage or the dysfunction of the peripheral nervous system.The incidence of PNP is relatively high and increases with age,and PNP has significant impact on patients'quality of life.Common syndromes associated with PNP include postherpetic neuralgia,painful diabetic peripheral neuropathy,trigeminal neuralgia,and painful radiculopathy.Buyang Huanwu Decoction,originating from Wang Qingren's Yi Lin Gai Cuo(Corrections on the Errors of Medical Works during)the Qing Dynasty and mainly having the actions of replenishing qi and promoting blood circulation,removing stasis and unblocking collaterals,is primarily known as a representative formula for treating stroke due to qi deficiency and blood stasis.Nowadays,modern practitioners have extended its application in treating various multi-system diseases in internal medicine.This paper systematically reviewed clinical studies and pharmacological mechanisms of Buyang Huanwu Decoction in treating PNP over the past 20 years.The results indicated that the combination of herbs in Buyang Huanwu Decoction has multi-component,multi-target,and multi-pathway effects on repairing nerve damage,nourishing nerves,promoting nerve regeneration,and alleviating neuropathic pain.Buyang Huanwu Decoction shows significant efficacy in treating PNP syndromes caused by neuropathic damage resulting from various etiological factors.This article reviewed both clinical observation and basic research on Buyang Huanwu Decoction in treating PNP,aiming to provide references for the clinical treatment of PNP and to expand the clinical applications of Buyang Huanwu Decoction.
