Construction of Core Outcome Set for Clinical Research on Uyghur Medicine in Treating Psoriasis
10.13359/j.cnki.gzxbtcm.2025.06.006
- VernacularTitle:维吾尔医治疗银屑病临床研究核心指标集的构建
- Author:
Ruifang YU
1
;
Abuduwaiti JULAITI
;
Shaonan LIU
;
Genghang CHEN
;
Qian HUANG
;
Wufuer ZAITUGULI
;
Upur TURSON
;
Zhijian LI
;
Xinfeng GUO
Author Information
1. 广州中医药大学第二临床医学院,广东 广州 510405
- Keywords:
Uyghur medicine;
psoriasis;
core outcome set(COS);
ethnic medicine
- From:
Journal of Guangzhou University of Traditional Chinese Medicine
2025;42(6):1334-1339
- CountryChina
- Language:Chinese
-
Abstract:
Objective To construct the core outcome set(COS)for clinical research on Uyghur medicine in treating psoriasis by using internationally-recognized research methods,thus to aid the researchers in choosing the standardized outcomes and to enhance the quality of evidence from research findings.Methods A systematic retrieval of Chinese and English databases was conducted to collect outcomes from clinical studies,systematic reviews,and registered protocols of Uyghur medicine for treating psoriasis.An outcome pool was constructed based on the results of literature review.The outcomes were supplemented after qualitative surveys of patients and physicians,and then an initial list of outcomes was formed.Two rounds of Delphi surveys on the initial list were conducted for obtaining Likert scale ratings from different stakeholder groups to evaluate the importance of outcomes.After that,a consensus meeting was held to finalize the COS for clinical research on Uyghur medicine in treating psoriasis.Results The COS for clinical research on Uyghur medicine in treating psoriasis comprises six domains,totaling 14 outcomes.The 14 outcomes were psoriasis symptoms(psoriasis area and area severity index),skin manifestations(erythema,scaling,infiltration,etc.),investigator global assessment,patient global assessment,treatment satisfaction,health-related quality of life,recurrence rate,adverse events,drug adverse reactions,blood routine,urine routine,liver and kidney function,Uyghur medicine symptom assessment,and fluid changes.Conclusion The COS for clinical research on Uyghur medicine in treating psoriasis has been constructed,and will provide a reference for the selection of efficacy-evaluation outcomes and for the reporting of outcomes in related studies.
