Exploring the Acupoint Selection Patterns in Acupuncture Treatment for Cognitive Impairment in Alzheimer's Disease Based on Data Mining
10.13359/j.cnki.gzxbtcm.2025.05.022
- VernacularTitle:基于数据挖掘探究针灸治疗阿尔茨海默病认知障碍的选穴规律
- Author:
Ying ZHANG
1
;
Weina YANG
;
Zhe ZHANG
Author Information
1. 西安交通大学第一附属医院东院,陕西 西安 710089
- Keywords:
Alzheimer's disease;
cognitive impairment;
acupuncture;
acupoint selection patterns;
data mining
- From:
Journal of Guangzhou University of Traditional Chinese Medicine
2025;42(5):1187-1194
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the acupoint selection patterns in acupuncture treatment for cognitive impairment in Alzheimer's disease based on data mining technology,and to provide references for clinical practice.Methods Computer searches were conducted in major databases including the China National Knowledge Infrastructure(CNKI),Wanfang Academic Journal Full-Text Database(Wanfang),VIP China Science and Technology Journal Database(VIP),China Biology Medicine(CBM),PubMed,Web of Science,and Embase.Clinical research literature on acupuncture treatment for cognitive impairment in Alzheimer's disease from the inception of the databases to May 1,2024 was selected.Microsoft Excel 2019 was used to establish a database of acupuncture prescriptions,and SPSS Statistics 24.0 and SPSS Modeler 18.0 were used for association analysis and cluster analysis to explore the acupoint selection patterns in acupuncture treatment for cognitive impairment in Alzheimer's disease.Results A total of 48 articles were included,involving 73 acupoints with a total frequency of 327 uses.The analysis of acupoints showed that the selection of acupoints mainly focused on the governor vessel and head/neck regions.The top three most frequently used acupoints were Baihui(GV20),Sishencong(EX-HN1),and Shenting(GV24).The association rule analysis indicated that the acupoint groups with the highest confidence were Baihui-Dazhui(GV14),Baihui-Shenting,Baihui-Sishencong,Baihui-Neiguan(PC6),and Baihui-Shenshu(BL23).The high-frequency cluster analysis revealed four clusters:Sanyinjiao(SP6)-Benshen(GB13),Shenmen(HT7)-Yintang(EX-HN3)-Taichong(LR3)-Fenglong(ST40)-Shenshu-Dazhui(GV14),Taixi(KI3)-Neiguan-Zusanli(ST36)-Guanyuan(CV4),and Fengchi(GB20)-Shenting.Conclusion In acupuncture treatment for cognitive impairment in Alzheimer's disease,acupoint selection mainly focuses on the governor vessel and head/neck regions.The combination of"Baihui-Sishencong-Shenting-Fengchi"can be used as the core acupoint selection in clinical treatment,and it can be adjusted based on syndrome differentiation and treatment in clinical practice.
