Clinical Observation on Acupuncture Combined with Western Medicine in the Treatment of Rheumatoid Arthritis Complicated with Mild Anemia Under the Guidance of"Dongyuan Acupuncture"
10.13359/j.cnki.gzxbtcm.2025.04.016
- VernacularTitle:"东垣针法"指导下针刺配合西药治疗类风湿关节炎伴轻度贫血的临床观察
- Author:
Fengzhi TAN
1
;
Min YU
;
Longlin ZHANG
Author Information
1. 广州中医药大学研究生院,广东 广州 510006;广州中医药大学第一附属医院重庆医院风湿病科,重庆 400700
- Keywords:
Dongyuan acupuncture;
acupuncture;
rheumatoid arthritis;
mild anemia;
clinical observation
- From:
Journal of Guangzhou University of Traditional Chinese Medicine
2025;42(4):907-913
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the clinical efficacy of acupuncture combined with western medicine in the treatment of rheumatoid arthritis(RA)complicated with mild anemia under the guidance of"Dongyuan acupuncture".Methods A total of 80 cases of patients definitively diagnosed as RA complicated with mild anemia of deficiency of qi and blood were selected and randomly divided into the observation group and the control group according to the random number table method,those who were admitted to the wards and outpatient clinics of the Department.of Rheumatology,Chongqing Hospital of The First Affiliated Hospital of Guangzhou University of Chinese Medicine from February 2024 to September 2024,with 40 cases in each group.The control group was given conventional treatment with western medicines,while the observation group was additionally treated with acupuncture under the guidance of"Dongguan acupuncture".The course of treatment covered four consecutive weeks.After one month of treatment,the clinical efficacy of the two groups was evaluated,and the changes in traditional Chinese medicine(TCM)syndrome scores and Visual Analogue Scale(VAS)of pain scores,as well as Disease Activity Scores(DAS-28)before and after treatment were observed in the two groups.The changes of rheumatoid factor(RF),C-reactive protein(CRP),erythrocyte sedimentation rate(ESR),red blood cell count(RBC),and hemoglobin(Hb)levels before and after treatment were compared between the two groups.The safety and incidence of adverse reactions in the two groups were also evaluated.Results(1)After treatment,the TCM syndrome scores of the patients in the observation group were improved significantly(P<0.05),and the improvement in the observation group was significantly superior to that in the control group,the difference being statistically significant(P<0.05).(2)After treatment,the VAS scores and DAS-28 scores of the patients in the two groups were improved significantly(P<0.05),and the improvement in the observation group was significantly superior to that in the control group,the difference being statistically significant(P<0.05).(3)After treatment,the RF,CRP,and ESR levels of patients in the two groups were improved significantly(P<0.05),and the improvement in the observation group was significantly superior to that in the control group,the difference being statistically significant(P<0.05);after treatment,there was a significant improvement in the RBC level of the observation group(P<0.05),but the difference was not statistically significant when compared with the control group(P>0.05);after treatment,the Hb level of patients in the two groups were improved significantly(P<0.05),and the improvement in the observation group was significantly superior to that in the control group,the difference being statistically significant(P<0.05).(4)The total effective rate was 95.00%(38/40)in the observation group and 87.50%(35/40)in the control group,and the efficacy of the observation group was superior to that of the control group,the difference being statistically significant(P<0.05).(5)The incidence of adverse reactions was 7.50%(3/40)in the observation group and 27.50%(11/40)in the control group,the incidence of adverse reactions in the observation group was significantly lower than that in the control group,the difference being statistically significant(P<0.05).Conclusion Under the guidance of"Dongyuan acupuncture",the application of acupuncture combined with western medicine in the treatment of RA complicated with mild anemia can not only realize the complementarity of acupuncture and medicine,improve the clinical efficacy,reduce the level of inflammatory factors,and significantly alleviate the joint symptoms of the patients,but also increase the level of blood cells,improve the anemia condition of the patients and have fewer adverse reactions,thus enhancing their quality of life.