Data Mining of Medication Rules of Chinese Herbal Medicine in Treating Polycystic Ovary Syndrome of Liver Stagnation Type Based on Ancient and Modern Medical Record Cloud Platform
10.13359/j.cnki.gzxbtcm.2025.01.038
- VernacularTitle:基于古今医案云平台挖掘中药治疗肝郁型多囊卵巢综合征的用药规律
- Author:
Shuying CHEN
1
;
Juanzhen XUE
;
Naiping WANG
;
Chunjing ZHAO
Author Information
1. 广州中医药大学东莞医院,广东东莞 523000
- Keywords:
polycystic ovary syndrome;
liver stagnation;
Ancient and Modern Medical Record Cloud Platform;
soothing liver and invigorating spleen;
nourishing liver and kidney;
Bupleuri Radix;
Paeoniae Radix Alba;
Angelicae Sinensis Radix
- From:
Journal of Guangzhou University of Traditional Chinese Medicine
2025;42(1):254-259
- CountryChina
- Language:Chinese
-
Abstract:
Objective Based on the Ancient and Modern Medical Record Cloud Platform,the medication rules of Chinese herbal medicine for the treatment of polycystic ovary syndrome(PCOS)of liver stagnation type were explored.Methods From database inception till December 2023,the medical records of TCM in treating PCOS of liver stagnation type were retrieved from the databases of China National Knowledge Infrastructure(CNKI),China Science and Technology Journal Database(VIP),Wanfang Data Knowledge Service Platform(Wangfang).After that,the data of prescription and TCM syndrome type were extracted,and then a database was constructed.The Ancient and Modern Medical Record Cloud Platform(V2.3.7)was used to conduct statistical analysis of relevant types of liver stagnation,occurrence frequency of Chinese herbal medicines,and the properties and efficacy of Chinese herbal medicines,as well as correlation analysis and clustering analysis for Chinese herbal medicines.The core prescriptions were mined by complex network analysis.Results A total of 108 prescriptions were included in this study,involving 174 Chinese herbal medicines.The syndrome of kidney deficiency and liver stagnation was most frequently seen,and Angelicae Sinensis Radix and Bupleuri Radix were the Chinese herbal medicines used most frequently.The Chinese herbal medicines usually have the meridian tropism of liver,spleen and kidney meridians,and most of them were mild and sweet in the proterties.The Chinese herbal medicines usually have the actions of soothing liver and alleviating depression.A total of 17 herbal groups such as"Angelicae Sinensis Radix-Paeoniae Radix Alba"and"Bupleuri Radix-Paeoniae Radix Alba"were obtained after association analysis,and the cluster analysis yielded four clustering combinations of Chinese herbal medicine.The core prescription was composed of Bupleuri Radix,Paeoniae Radix Alba,Angelicae Sinensis Radix,Poria,Glycyrrhizae Radix et Rhizoma,Cuscutae Semen,Rehmanniae Radix Praeparata,Cyperi Rhizoma,and Atractylodis Macrocephalae Rhizoma.Conclusion Chinese medicine treatment for PCOS of liver stagnation type focuses on soothing liver and invigorating spleen,nourishing liver and kidney,thus to harmonize qi and blood,and thoroughfare vessel and conception vessel.
