Discussion on Traditional Chinese Medicine Treatment for Patients with Insulin Resistance in Type 2 Diabetes Mellitus Based on the Theory of Yang Deficiency Causing Diabetes
10.13359/j.cnki.gzxbtcm.2025.01.036
- VernacularTitle:基于阳虚致消理论探讨2型糖尿病胰岛素抵抗患者的中医治疗
- Author:
Huiqing WANG
1
;
Changcai XIE
;
Hanlin WANG
;
Lihong YIN
;
Wenfei FAN
Author Information
1. 广州中医药大学第二临床医学院,广东广州 510006
- Keywords:
type 2 diabetes mellitus;
insulin resistance;
yang deficiency causing diabetes;
insulin signal transduction;
insulin secretion function;
traditional Chinese medicine treatment
- From:
Journal of Guangzhou University of Traditional Chinese Medicine
2025;42(1):243-248
- CountryChina
- Language:Chinese
-
Abstract:
Type 2 diabetes mellitus(T2DM)is a metabolic disease characterized by insulin resistance,and is one of the most common chronic non-communicable diseases worldwide.In the field of traditional Chinese medicine(TCM),yang deficiency causing diabetes is one of the important pathogenetic mechanisms of T2DM and contributes to the core pathological basis of insulin resistance.Guided by the theory of yang deficiency causing diabetes,this paper reviewed the relevant domestic literature issued in recent years,sorted out western medical pathogenesis and treatment for insulin resistance in T2DM,TCM theory of yang deficiency causing diabetes and its clinical application,and the clinical efficacy of TCM for the treatment of insulin resistance,and then explored the applicability of theory of yang deficiency causing diabetes for TCM treatment of insulin resistance in T2DM.It is concluded that TCM treatment for insulin resistance in T2DM based on the theory of yang deficiency causing diabetes has significant efficacy and advantages,for it realizes the integration of advantages of TCM and western medicine and achieves the synergistic actions through keeping the scientific nature and standardization of western medicine and by maintaining the advantages of holism and individualization of TCM treatment.TCM treatment for insulin resistance is effective on improving insulin signal transduction,insulin secretion function and other related metabolic abnormalities indicators through multiple pathways and targets,thus to improve the health status of the body.TCM treatment for insulin resistance exerts good safety and tolerance,and can reduce the incidence of adverse reactions caused by western medicine.However,the research on TCM treatment for insulin resistance still has the insufficiencies such as low quality of clinical trials,unclear therapeutic mechanism,and lack of innovation and pioneering.Further relevant research needs to be carried out in-depth,so as to provide a scientific basis for TCM to play a greater role in preventing and treating metabolic diseases.
