Study on the differences in active components, characteristic components and therapeutic functions between Hedysari Radix and Astragali Radix
10.3760/cma.j.cn115398-20250107-00082
- VernacularTitle:红芪与黄芪活性成分、特征成分及功能主治差异性研究
- Author:
Huilong FENG
1
;
Difei TANG
;
Bing ZHAO
;
Hong LI
;
Taoping LIU
;
Xiaochuan LUO
Author Information
1. 中国科学院过程工程研究所生物药制备与递送全国重点实验室，北京 100190
- Keywords:
Hedysari Radix;
Astragali Radix;
Active ingredients;
Characteristic components;
Therapeutic functions;
Antioxidant activity
- From:
International Journal of Traditional Chinese Medicine
2025;47(12):1732-1738
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the differences in active components between Hedysari Radix and Astragali Radix; To explore the material basis and therapeutic functions of Hedysari Radix in promoting blood circulation and nourishing blood.Methods:The research materials used in this study were Hedysari Radix and Astragali Radix from Wudu District, Longnan City, Gansu Province. The contents of seven resource-based components-total sugars, total polyphenols, total flavonoids, crude proteins, total saponins, total alkaloids, and total dietary fiber were measured according to standard methods. Additionally, an HPLC method was established to quantify 21 active compounds. In vitro antioxidant experiments were conducted to assess the scavenging ability of DPPH and ABTS free radicals.Results:The contents of resource-based components in Hedysari Radix were higher than in Astragali Radix. Among the 21 active components, the characteristic active components of Astragali Radix, such as calycosin, formononetin, calycosin glucoside and so on, were high in contents. The contents of paeoniflorin and Medicinol in Astragali Radix were low or not detected, and the contents in Hedysari Radix were 98.828 μg/g and 103.986 μg/g, and the antioxidant capacity was also better than Astragali Radix.Conclusions:The basic components of Hedysari Radix for promoting blood circulation and nourishing blood are paeoniflorin, Medilac, vanillic acid, ferulic acid and formononetin, which can provide a scientific basis for the determination of the characteristic components and the improvement of the main functions of Hedysari Radix.
